Experimental tailor-made vaccines targeting melanoma patients' individual genetic mutations have given encouraging preliminary results, researchers have said. The clinical test on three patients with this form of aggressive skin cancer in an advanced stage is unprecedented in the United States. The vaccines appear to boost the number and diversity of T-cells, which are key to the human immune system and attack tumors, researchers said in a report published Thursday in the journal Science. Last year 76,000 Americans were diagnosed with melanoma and nearly 10,000 died of it, according to the National Cancer Institute.
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